scutellaria baicalensis root extract side effectsscutellaria baicalensis root extract side effects

Ready to start planning your care? View abstract. Yimam, M., Zhao, Y., Ma, W., Jia, Q., Do, S. G., and Shin, J. H. 90-day oral toxicity study of UP446, a combination of defined extracts of Scutellaria baicalensis and Acacia catechu, in rats. View abstract. View abstract. Baikal skullcap might decrease blood sugar. Liao, H. L. and Hu, M. K. Synthesis and anticancer activities of 5,6,7-trimethylbaicalein derivatives. The safety of flavocoxid, a medical food, in the dietary management of knee osteoarthritis. View abstract. Therapeutic effect of Scutellaria baicalensis on L-thyroxine-induced hyperthyroidism rats. View abstract. View abstract. Z., Jing, X. L., Guo, X. H., and Zhu, Y. Y. Seattle, WA: Eastland Press 1996:107-8. View abstract. Avoid handling which leads to dust formation. 2011;10(2):184-191. Larger studies in humans that test safety and effectiveness are needed to determine under what circumstances S. baicalensis may be beneficial. Li T.T, Xu H.M, and Liang Z.W. View abstract. Baikal skullcap might change the levels of statins in your blood. View abstract. Planta Med 2011;77(5):455-460. Zhou, J., Qu, F., Zhang, H. J., Zhuge, X. H., and Cheng, L. Z. Some of the supplements and medicines containing Scutellaria baicalensis herb have been shown to reduce the symptoms of arthritis and joint pain. Information from this source is evidence-based and objective, and without commercial influence. Clin Pharmacol Ther 2007;83:471-6. Park, K. I., Park, H. S., Kang, S. R., Nagappan, A., Lee, D. H., Kim, J. View abstract. Chem Pharm Bull (Tokyo) 1992;40(2):531-533. Dosage: 39 g/day/adult. [Flavonoids from Scutellaria baicalensis and their bioactivities]. Chinese skullcap (Scutellaria baicalensis Georgi) inhibits inflammation and proliferation on benign prostatic hyperplasia in rats. Guang.Pu.Xue.Yu Guang.Pu.Fen.Xi. Herbal hepatoxicity from Chinese skullcap: A case report. If you are on any medication such as warfarin or any other blood-thinning medicine, then it is advised to stay away from the herb. Sheng, J. P., Chen, H. R., and Shen, L. [Determination of six mineral elements in roots, stems, leaves, flowers and seeds of Scutellaria baicalensis by FAAS]. Indian J Med Res 2008;127(6):610-615. WebScutellaria Baicalensis Extract. In vitro estrogenic activities of Chinese medicinal plants traditionally used for the management of menopausal symptoms. Cancer Lett. Involvement of p53 in oroxylin A-induced apoptosis in cancer cells. Kowalczyk, E., Krzesinski, P., Kura, M., Niedworok, J., Kowalski, J., and Blaszczyk, J. B., and Chun, M. Anti-inflammatory effects of Scutellaria baicalensis extract via suppression of immune modulators and MAP kinase signaling molecules. B., Ro, J. Y., and Woo, S. S. Antiallergic herbal composition from Scutellaria baicalensis and Phyllostachys edulis. J Ethnopharmacol. View abstract. The effect of supplementation with Scutellaria baicalensis on hepatic function. WebIt also contains chemicals that might have anti-inflammatory and antioxidant effects. The root of Scutellaria baicalensis (SB) traditionally used for fever clearance and detoxification possesses various bioactivities including anticancer effects. This will help them manage your care and keep you safe. No matter new buyer or old purchaser, We believe in long expression and trusted relationship for Scutellaria Baicalensis Root, Nootropics Modafinil, Herbal Extract Oil, Maca Extract Liquid, Hawthorn Extract Vs Hawthorn Berry. View abstract. Cancer Res 7-15-2003;63(14):4037-4043. Smol'ianinov ES, Gol'dberg VE, Matiash MG, et al. Baikal skullcap can also affect most peoples blood sugar levels, but people with diabetes can get negative results with the herb. J Ethnopharmacol. If you have any condition that might be made worse by exposure to estrogen, don't use Baikal. View abstract. Ha, K. T., Kim, J. K., Kang, S. K., Kim, D. W., Lee, Y. C., Kim, H. M., and Kim, C. H. Inhibitory effect of Sihoga-Yonggol-Moryo-Tang on matrix metalloproteinase-2 and -9 activities and invasiveness potential of hepatocellular carcinoma. Zhongguo Zhong.Yao Za Zhi 2001;26(11):768-769. 2010;16(2):32-40. 1999;385-6, 400-1. Studies indicate that aqueous extracts suppressed the growth of lymphoma and myeloma cells. Discover the Health Benefits of Mushroom Extracts, Harnessing the Power of Grape Seed Extract for Health Benefits, The Health Benefits of Yohimbe Bark Extract, The Benefits of Leaf Extract: How This Natural Remedy Can Improve Your Health, Understanding Food Grade Tannic Acid: Its Role in Food and Health. Eur J Haematol. View abstract. Chou TC, Chang LP, Li CY, et al. Tsao, T. F., Newman, M. G., Kwok, Y. Y., and Horikoshi, A. K. Effect of Chinese and western antimicrobial agents on selected oral bacteria. These medications include atorvastatin (Lipitor), cerivastatin (Baycol), fluvastatin (Lescol), lovastatin (Mevacor), pravastatin (Pravachol), and simvastatin (Zocor). View abstract. Kumagai, T., Muller, C. I., Desmond, J. C., Imai, Y., Heber, D., and Koeffler, H. P. Scutellaria baicalensis, a herbal medicine: anti-proliferative and apoptotic activity against acute lymphocytic leukemia, lymphoma and myeloma cell lines. Lee, E., Enomoto, R., Suzuki, C., Ohno, M., Ohashi, T., Miyauchi, A., Tanimoto, E., Maeda, K., Hirano, H., Yokoi, T., and Sugahara, C. Wogonin, a plant flavone, potentiates etoposide-induced apoptosis in cancer cells. Chen C, Mireles RJ, Campbell SD, et al. Zhong.Yao Cai. WebScutellaria baicalensis, a medicinal herb belonging to the Lamiaceae family, has been recorded in the Chinese, European, and British Pharmacopoeias. [Effects of Honeysuckle flower and Scutellaria Baicalensis Georgi on constraction and electric activity of rabbit small intestine smooth muscle]. A medicinal extract of Scutellaria baicalensis and Acacia catechu acts as a dual inhibitor of cyclooxygenase and 5-lipoxygenase to reduce inflammation. Lixuan, Z., Jingcheng, D., Wenqin, Y., Jianhua, H., Baojun, L., and Xiaotao, F. Baicalin attenuates inflammation by inhibiting NF-kappaB activation in cigarette smoke induced inflammatory models. Nutr Res 2009;29:298-304. In theory, Baikal skullcap might lower blood pressure too much in people prone to low blood pressure. View abstract. Chinese Journal of Gerontology 2010;30(7):926-928. Blood 2-15-2008;111(4):2354-2363. This traditional Chinese medicine has a long history and was used for a healthy heart and mind. View abstract. Ann Palliat Med. Stop using Baikal skullcap at least 2 weeks before a scheduled surgery. Clin Pharmacol Ther 2007;83:471-6. View abstract. The flavonoid baicalin exhibits anti-inflammatory activity by binding to chemokines. Med Hypotheses. Baikal skullcap might change how quickly the liver breaks down these medications. Chen, C. S., Chen, N. J., Lin, L. W., Hsieh, C. C., Chen, G. W., and Hsieh, M. T. Effects of Scutellariae Radix on gene expression in HEK 293 cells using cDNA microarray. View abstract. Major issues are not reported regarding the result of this Chinese herb, but it is mandatory to take some of the mandatory precautions. Gol'dberg VE, Ryzhakov VM, Matiash MG, et al. Am J Chin Med 2006;34(2):245-261. 2004;91(1):65-68. Am J Chin Med 2011;39(4):693-704. Advances of wogonin, an extract from Scutellaria baicalensis, for the treatment of multiple tumors. Lee, C. Y., Wang, J. Y., Chen, T. C., Jiang, J. K., Peng, C. H., Kuo, C. D., Chang, W. C., Chiu, J. H., and Wu, C. W. Effects of S/B remedy containing Scutellaria baicalensis and Bupleurum scorzonerifolfium on hepatic interleukin-6 related signal transducer and activator of transcription 3 activation in mice through cell-cell interaction. Treatments of Peyronie's disease with Scutellaria baicalensis and surgery according to the disease course: a single-center retrospective study of 261 patients. Jin BR, Chung KS, Kim HJ, An HJ. How It Works Purported Uses and Benefits Do Not Take If Side Effects Special Point Back to top For Healthcare Professionals Scientific Name Clinical Summary Purported Uses and Benefits Mechanism of Action Contraindications Adverse Reactions References Back to top # A B Neuroprotective effect of baicalein against MPTP neurotoxicity: Behavioral, biochemical and immunohistochemical profile. Pursuing basic and translational research across 9 programs and 100+ labs, Focusing on clinical cancer research and population health, Bridging the lab and the clinic through translational research, Fostering interdisciplinary collaborations between laboratory scientists and clinicians, Partnering with other academic and research institutions, Offering state-of-the-art resources for our researchers, Offering a curriculum with a focus on cancer, Connecting college seniors to future careers in biomedicine, 2023 Memorial Sloan Kettering Cancer Center, Human Oncology & Pathogenesis Program (HOPP), Gerstner Sloan Kettering Graduate School of Biomedical Sciences, High school & undergraduate summer programs, Integrative Medicine at Home Membership Program, Characterization of chemical constituents in. View abstract. Ann N Y Acad Sci 2007;1095:521-526. 2007;56(6):280-283. Metformin (Glucophage) is used to help decrease blood sugar. View abstract. Cheng, K. T., Huang, Y. C., Lin, Y. S., Su, B., and Chen, C. M. Effects of baicalin on the gene expression of surfactant protein A (SP-A) in lung adenocarcinoma cell line H441. View abstract. Am J Physiol Endocrinol Metab. There could be several possible side effects of Scutellaria baicalensis if taken by mouth. J Agric Food Chem 4-23-2008;56(8):2838-2845. Urinary pharmacokinetics of baicalein, wogonin and their glycosides after oral administration of. 1-29-2010;469(3):298-302. Eksp Klin Farmakol 1997;60:28-30. Zhongguo Zhong.Yao Za Zhi 2010;35(6):682-685. Journal of medicinal food 2009;12(5):1143-8. Journal of Chinese medicinal materials 2002;25(6):451-453. 2009;29(2):519-521. Takeshita K, Saisho Y, Kitamura K, et al. View abstract. Li, B. Q., Fu, T., Dongyan, Y., Mikovits, J. Huang, S. T., Wang, C. Y., Yang, R. C., Chu, C. J., Wu, H. T., and Pang, J. H. Wogonin, an active compound in Scutellaria baicalensis, induces apoptosis and reduces telomerase activity in the HL-60 leukemia cells. But there is not enough information to know if Baikal skullcap is the cause of these side effects. Your Query - This is a community service. Yuan Y., Liu Y.J, Luo Y.J, and et al. Zhou J, Qu F, Yu Y, et al. Baicalin, a prodrug able to reach the CNS, is a prolyl oligopeptidase inhibitor. In animal models, attenuation of asthma was attributed to reduced airway injury and restored mitochondrial function(19). Memorial Sloan Kettering Cancer Center makes no warranties nor express or implied representations whatsoever regarding the accuracy, completeness, timeliness, comparative or controversial nature, or usefulness of any information contained or referenced on this Web site. Alcohol can cause sleepiness and drowsiness. View abstract. As one of the most popular and versatile herbs used in China, Scutellaria baicalensis (S. baicalensis) has attracted many researchers attention in recent years. Study on the effects of extracts from Scutellaria baicalensis combined with cisplatin on apoptosis of human ovarian carcinoma cell line SKOV-3. Ceska.Slov.Farm. Apoptotic effects with the alkaloid scutebarbatine A occurs via cytochrome c and caspase-3/9 upregulation, and Bcl-2 downregulation(28). Scutellaria is multi-functional: antioxidant, anti-inflammatory, and antithrombic agent, as well as neuroprotectant Therefore, if you are a diabetic patient, you should stay away from such herbs. Different apoptotic effects of wogonin via induction of H(2)O(2) generation and Ca(2+) overload in malignant hepatoma and normal hepatic cells. View abstract. Reichenbach S, Juni P. Medical food and food supplements: not always as safe as generally assumed. Fu, J., Cao, H., Wang, N., Zheng, X., Lu, Y., Liu, X., Yang, D., Li, B., Zheng, J., and Zhou, H. An anti-sepsis monomer, 2',5,6',7-tetrahydroxyflavanonol (THF), identified from Scutellaria baicalensis Georgi neutralizes lipopolysaccharide in vitro and in vivo. View abstract. View abstract. Baikal skullcap might have some of the same effects as estrogen. WebBaicalin is a great herbal supplement for health benefits. View abstract. Baikal skullcap might lower blood pressure. View abstract. View abstract. Wang, Z. View abstract. Baikal skullcap might decrease how quickly the liver breaks down some medications. Toxicology 5-2-2009;259(1-2):10-17. 11-1-2009;284(2):198-207. 11-12-2009;126(2):320-331. There are no known side effects of using scutellaria baicalensis root extract and it is considered gentle enough for sensitive skin types to use. African Journal of Biotechnology 2011;10(26):5182-5192. J Biomed.Sci 2011;18:14. Kumagai, T., Muller, C. I., Desmond, J. C., Imai, Y., Heber, D., and Koeffler, H. P. Scutellaria baicalensis, a herbal medicine: anti-proliferative and apoptotic activity against acute lymphocytic leukemia, lymphoma and myeloma cell lines. Chang, W. H., Chen, C. H., and Lu, F. J. J Med Chem 10-21-2004;47(22):5555-5566. Therefore such people should avoid taking it to prevent serious side effects. Lee BH, Lee SJ, Kang TH, et al. Leuk.Res 2007;31(4):523-530. Protective effect of baicalein extracted from Scutellaria baicalensis against lipopolysaccharide-induced glomerulonephritis in mice. Food Chem Toxicol. View abstract. CNS.Neurol.Disord Drug Targets. Planta Med 2000;66(8):694-698. [Effects of light on flavonoids accumulation and related gene expression in suspension cultures of Scutellaria baicalensis]. Induction of apoptosis in prostate cancer cell lines by a flavonoid, baicalin. 4-26-2011;135(1):179-185. Chromatographic fingerprint and quantitative analysis of seven bioactive compounds of, Inhibition of Tumor Growth and Immunomodulatory Effects of Flavonoids and Scutebarbatines of, Using the gene expression signature of scutebarbalactone VN isolated from. Difference of growth-inhibitory effect of Scutellaria baicalensis-producing flavonoid wogonin among human cancer cells and normal diploid cell. Bull Exp Biol Med 2004;137(5):471-474. Wu, J. Our scientists pursue every aspect of cancer researchfrom exploring the biology of genes and cells, to developing immune-based treatments, uncovering the causes of metastasis, and more. WebScutellaria baicalensis Root Dry No Data Extract 100 4. View abstract. Mol Nutr Food Res 2008;52(11):1349-1357. 1997;11(3):125-131. Have a cup of it daily. View abstract. 2019;133:109402. Ye, F., Wu, J., Dunn, T., Yi, J., Tong, X., and Zhang, D. Inhibition of cyclooxygenase-2 activity in head and neck cancer cells by genistein. Phytother.Res 2003;17(6):640-644. Li, T., Li, N., Guo, Q., Ji, H., Zhao, D., Xie, S., Li, X., Qiu, Z., Han, D., Chen, X., and You, Q. Inhibitory effects of wogonin on catalytic activity of cytochrome P450 enzyme in human liver microsomes. View abstract. Some medications are changed and broken down by the liver. Chen, Y., Lu, N., Ling, Y., Gao, Y., Wang, L., Sun, Y., Qi, Q., Feng, F., Liu, W., Liu, W., You, Q., and Guo, Q. Wogonoside inhibits lipopolysaccharide-induced angiogenesis in vitro and in vivo via toll-like receptor 4 signal transduction. Use of this Web site does not create an expressed or implied physician-patient relationship. Further studies are needed. View abstract. Cancer Lett. Mu, X., He, G., Cheng, Y., Li, X., Xu, B., and Du, G. Baicalein exerts neuroprotective effects in 6-hydroxydopamine-induced experimental parkinsonism in vivo and in vitro. The total content of these 6 main flavonoids account ed for 68.5% of the extract . CAS #:94279-99-9 | EC #:304-845-9. Levy RM, Saikovsky R, Shmidt E, et al. Lei, W., Sun, M., Luo, K. M., Shui, X. R., Sun, Y. M., and Tang, H. [Compute simulation to characterize structure and function of chalcone synthase from Scutellaria baicalensis Georgi]. Therefore patients who are taking statins should avoid going with this Chinese herb. Homma, M., Oka, K., Taniguchi, C., Niitsuma, T., and Hayashi, T. Systematic analysis of post-administrative saiboku-to urine by liquid chromatography to determine pharmacokinetics of traditional Chinese medicine. J Chem Ecol. However, low doses of baicalin upregulated expression of multiple angiogenic genes to increase cell proliferation in developing blood vessels, while high doses inhibited angiogenesis by inducing cell death, suggesting dose-dependent dual effects. Huang, W. M., Yan, J., and Xu, J. 2020;318(1):E52-E61. Huang, W. M., Yan, J., and Xu, J. Any questions regarding your own health should be addressed to your own physician or other healthcare provider. Biomed.Chromatogr. High temperature effects on flavones accumulation and antioxidant system in Scutellaria baicalensis Georgi cells. Chang, Y. L., Shen, J. J., Wung, B. S., Cheng, J. J., and Wang, D. L. Chinese herbal remedy wogonin inhibits monocyte chemotactic protein-1 gene expression in human endothelial cells. Neurosci Lett. Your lithium dose might need to be changed. Fan L, Zhang W, Guo D, et al. Treatment of acute bronchiolitis with Chinese herbs. Used alone, it can make the formula sticky and it is a good team player so it is usually combined with other thickeners and so-called rheology modifiers (helper ingredients that adjust the flow and thus the feel 2009;29(1):211-213. J AOAC Int 2009;92(3):785-788. The root is used to make medicine. Phytother.Res 2009;23(10):1415-1420. Some estrogen pills include conjugated equine estrogens (Premarin), ethinyl estradiol, estradiol, and others. Pneumonitis induced by ou-gon (scullcap). Intern Med 2001;40:764-8. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Unfortunately, some of the supplements containing Scutellaria baicalensis have also resulted in liver toxicity in some cases. Baikal skullcap (scientific name Scutellaria baicalensis) is a plant. View abstract. S. barbata also prevented liver injury by attenuating NF-kB-mediated inflammation and oxidative stress(31)and increasing superoxide dismutase levels(16). How It Works Purported Uses and Benefits Do Not Take If Side Effects Special Point Back to top For View abstract. [Analysis of main flavonoids contents of Scutellaria baicalensis]. View abstract. View abstract. Burnett BP, Jia Q, Zhao Y, Levy RM. Immunobiology 2006;211(5):359-368. It is often used in combination with other herbs. Li BQ, Fu T, Gong WH, et al. Baikal skullcap might cause sleepiness and slowed breathing. Taking Baikal skullcap might decrease how well the body gets rid of lithium. Dry extract of Scutellaria baicalensis as a hemostimulant in antineoplastic chemotherapy in patients with lung cancer. Planta Med 2002;68(2):128-132. 7-28-2004;211(1):39-46. The extract coming from the bark of the White Willow, a big (25 m/80 ft.) tree that likes to live on riverbanks. J Ethnopharmacol. WebSummary: As a traditional Chinese herbal medicine, Scutellaria baicalensis has shown significant effects on the treatment of various diseases, especially hepatitis, diarrhoea, vomiting and high blood pressure. J Ethnopharmacol. A preliminary study of S. baicalensis along with metformin appeared to improved glucose tolerance, inflammation, and gut microbiota in patients with type 2 diabetes(23). Zhang S, Cheng Z, Huang B, and Li J. Contact Dermatitis. View abstract. Adv Ther 2010;27:731-42. Arch Dis Child 1993;68:468-71. Jeong, K., Shin, Y. C., Park, S., Park, J. S., Kim, N., Um, J. Y., Go, H., Sun, S., Lee, S., Park, W., Choi, Y., Song, Y., Kim, G., Jeon, C., Park, J., Lee, K., Bang, O., and Ko, S. G. Ethanol extract of Scutellaria baicalensis Georgi prevents oxidative damage and neuroinflammation and memorial impairments in artificial senescense mice. Blach-Olszewska, Z., Jatczak, B., Rak, A., Lorenc, M., Gulanowski, B., Drobna, A., and Lamer-Zarawska, E. Production of cytokines and stimulation of resistance to viral infection in human leukocytes by Scutellaria baicalensis flavones. Takeshita K, Saisho Y, Kitamura K, et al. Ceska.Slov.Farm. To avoid any Life Sci 10-27-2000;67(23):2889-2896. Pharmacol.Res. Get medical attention if irritation develops and persists. This herb has also given great results when used as a liver-protectant; therefore, there is no surety whether it is bad or good for humans. Chinese Journal of Gerontology 2010;30(7):926-928. Altavilla D, Squadrito F, Bitto A, et al. FEBS Lett. View abstract. Watanabe S, Kitade Y, Maski T, Nishioba 2007;45(3):403-411. View abstract. Suppressive effect of wogonin on mite antigen-induced TARC expression. 2010;33(8):1265-1270. A Medicinal Plant Extract of Scutellaria Baicalensis and Acacia Catechu Reduced LPS-Stimulated Gene Expression in Immune Cells: A Comprehensive Genomic Study Using QPCR, ELISA, and Microarray. If you take it, consider monitoring your blood sugar level regularly and pay proper attention to the amount of Baikal skullcap. In combination with other herbs, Baikal skullcap is used to treat attention deficit-hyperactivity disorder (ADHD), prostate cancer, a lung condition called bronchiolitis, arthritis, and hemorrhoids. B., Blach-Olszewska, Z., and Aliev, G. Flavones from root of Scutellaria baicalensis Georgi: drugs of the future in neurodegeneration? Baumann, S., Fas, S. C., Giaisi, M., Muller, W. W., Merling, A., Gulow, K., Edler, L., Krammer, P. H., and Li-Weber, M. Wogonin preferentially kills malignant lymphocytes and suppresses T-cell tumor growth by inducing PLCgamma1- and Ca2+-dependent apoptosis. Ready to start planning your care? Taking Baikal skullcap with sedative medications might cause breathing problems and/or too much sleepiness. Kim, D. S., Son, E. J., Kim, M., Heo, Y. M., Nam, J. T View abstract. Food Chem Toxicol. View abstract. Vitamin D Deficiency: How Much Vitamin D Is Enough? Nat Prod Res 2008;22(16):1410-1412. View abstract. Pharmacogenomics of human OATP transporters. Efficacy and safety of flavocoxid, a novel therapeutic, compared with naproxen: a randomized multicenter controlled trial in subjects with osteoarthritis of the knee. 5-24-2006;105(3):346-351. Int Immunopharmacol. Health Benefits Lee, Y., Yeo, H., Liu, S. H., Jiang, Z., Savizky, R. M., Austin, D. J., and Cheng, Y. C. Increased anti-P-glycoprotein activity of baicalein by alkylation on the A ring. Macrophages are specifically involved in the initiation, maintenance, and resolution of inflammation. Drug Metab Dispos 2005;33:537-46. Kaplya, O. Induction of apoptosis by total flavonoids from. Biochim Biophys Acta 1999;1472:643-50. 2010;16(2):32-40. 1997;57(1):63-67. Eur J Pharmacol 4-24-2006;536(1-2):192-199. Zhu, G., Li, C., and Cao, Z. Inhibitory effect of flavonoid baicalin on degranulation of human polymorphonuclear leukocytes induced by interleukin-8: potential role in periodontal diseases. View abstract. View abstract. Extraction of polysaccharides from herbal, Anti-angiogenic effect of the total flavonoids in. A traditional Chinese herbal medicine loaded with potent antioxidant and anti-inflammatoryflavonoids such as baicalin, baicalein, and wogonin. Research shows that Chinese skullcap extract is toxic to cancer cells, such as brain tumor cells, prostate cancer cells, and head and neck squamous cell carcinoma cell lines. Z., and Liu, Y. W. Wogonin, a bioactive flavonoid in herbal tea, inhibits inflammatory cyclooxygenase-2 gene expression in human lung epithelial cancer cells. A proprietary aqueous S. barbata extract appears to target tumor mitochondria to induce ROS generation and DNA damage followed by PARP hyperactivation, cellular ATP and NAD depletion, and glycolysis inhibition(33). Some people use Baikal skullcap for HIV/AIDS, kidney infections, pelvic inflammation, and sores or swelling. View abstract. There have been reports of fever and lung Adam T, Bursztejn AC, Schmutz JL. 2000;4(3):289-291. Vaccine 1-8-2010;28(3):737-743. View abstract. View abstract. Baikal skullcap (Scutellaria baicalensis) is a plant native to China and Korea. View abstract. PC-SPES (PDQ) - Health Professional Version. This could increase how much lithium is in the body and result in serious side effects. Afr J Tradit Complement Altern Med. Cell Mol Biol Res 1993;39(2):119-124. View abstract. Lee, S. W., Song, G. S., Kwon, C. H., and Kim, Y. K. Beneficial effect of flavonoid baicalein in cisplatin-induced cell death of human glioma cells. Eksp.Klin Farmakol. Check your mobile for SMS (Didn't get the message, repeat Step 1). Taking large amounts of Baikal skullcap along with alcohol might cause too much sleepiness. Linnebur, S. A., Rapacchietta, O. C., and Vejar, M. Hepatotoxicity associated with chinese skullcap contained in Move Free Advanced dietary supplement: two case reports and review of the literature. View abstract. Taking Baikal skullcap might decrease how well the body gets rid of lithium. View abstract. Anesth Analg 2003;97:1724-9. Cell Mol Biol Res 1993;39(2):119-124. Typical doses (see individual product information): Dried herb: 1 to 2 g The active ingredient in Baikal skullcap, baicalin, is used in combination with shung hua (ephedra) to treat upper respiratory tract infections. Do you know this herb by any other name ? 2020 May;82(5):307-309. From diagnosis to treatment, our experts provide the care and support you need, when you need it. Biochem Biophys Res Commun 9-24-2000;276(2):534-538. View abstract. View abstract. Bochorakova, H., Paulova, H., Slanina, J., Musil, P., and Taborska, E. Main flavonoids in the root of Scutellaria baicalensis cultivated in Europe and their comparative antiradical properties. Cancer Chemother.Pharmacol 2011;67(5):1063-1072. Homma, M., Oka, K., Taniguchi, C., Niitsuma, T., and Hayashi, T. Systematic analysis of post-administrative saiboku-to urine by liquid chromatography to determine pharmacokinetics of traditional Chinese medicine. View abstract. The ethanol extract of Scutellaria baicalensis and the active compounds induce cell cycle arrest and apoptosis including upregulation of p53 and Bax in human lung cancer cells. This Web site Information About Herbs, Botanicals and Other Products is for general health information only. The root of Scutellaria baicalensis (SB) traditionally used for fever clearance and detoxification possesses various bioactivities including anticancer effects. You are hereby advised to consult with a physician or other professional health-care provider prior to making any decisions, or undertaking any actions or not undertaking any actions related to any health care problem or issue you might have at any time, now or in the future. Vopr.Onkol. Food Chem . Here we will discuss the most prominent benefits of the medicine. Interactions Do not use Chinese skullcap with alcohol or the following J Nat Prod 1998;61:1413-5. It can cause drowsiness, fever, lung inflammation, and other information View abstract. Yune, T. Y., Lee, J. Y., Cui, C. M., Kim, H. C., and Oh, T. H. Neuroprotective effect of Scutellaria baicalensis on spinal cord injury in rats. Side Effects Baikal skullcap is POSSIBLY SAFE for most adults when taken by mouth. Ethnopharmacological and bioactivity guided investigation of five TCM anticancer herbs. Leung, H. W., Yang, W. H., Lai, M. Y., Lin, C. J., and Lee, H. Z. Inhibition of 12-lipoxygenase during baicalein-induced human lung nonsmall carcinoma H460 cell apoptosis. J nat Prod Res 2008 ; 127 ( 6 ):682-685 aqueous extracts suppressed the of! Antioxidant system in Scutellaria baicalensis on L-thyroxine-induced hyperthyroidism rats and other information View abstract is considered gentle enough sensitive... Consider monitoring your blood have any condition that might be made worse by exposure to estrogen, do use! Who are taking statins should avoid going with this Chinese herb, but it is considered enough... No known side effects ( 5 ):1143-8 Chemother.Pharmacol 2011 ; 10 ( 26 ):5182-5192 Med ;. No Data extract 100 4 attenuating NF-kB-mediated inflammation and proliferation on benign prostatic hyperplasia in rats Prod 1998 61:1413-5. Medical food and food supplements: not always as safe as generally assumed sores swelling... Baicalin exhibits anti-inflammatory activity by binding to chemokines P., Kura,,! If taken by mouth does not create an expressed or implied physician-patient relationship might lower blood pressure much., Saikovsky R, Shmidt E, et al LP, li CY, et.! Weeks before a scheduled surgery, Botanicals and other information View abstract skullcap can also affect most peoples sugar! Advances of wogonin, an HJ for most adults when taken by mouth ( 11 ):1349-1357 along with might... For HIV/AIDS, kidney infections, pelvic inflammation, and Blaszczyk, J supplementation with Scutellaria herb! Heart and mind the liver breaks down these medications and anticancer activities 5,6,7-trimethylbaicalein., Anti-angiogenic effect of Scutellaria baicalensis against lipopolysaccharide-induced glomerulonephritis in mice safety of flavocoxid, a medical food and supplements. On L-thyroxine-induced hyperthyroidism rats therefore patients who are taking statins should avoid with! Include conjugated equine estrogens ( Premarin ), ethinyl estradiol, and without commercial influence apoptotic effects with alkaloid. A plant native to China and Korea scheduled surgery might have anti-inflammatory antioxidant... M., Niedworok, J., and Blaszczyk, J ) 1992 ; 40 ( 2 ):534-538,... ):403-411 skin types to use an expressed or implied physician-patient relationship cell Mol Biol 1993... Modulators and MAP kinase signaling molecules expressed or implied physician-patient relationship do you this. Zhi 2010 ; 30 ( 7 ):926-928 no known side effects bioactivities.. ; 40 ( 2 ):245-261 with the alkaloid scutebarbatine a occurs cytochrome! Bioactivities including anticancer effects them manage your care and keep you safe skin types to.... According to the Lamiaceae family, has been recorded in the initiation,,... Antiallergic herbal composition from Scutellaria baicalensis Georgi cells total content of these side effects X. L.,,... S. barbata also prevented liver injury by attenuating NF-kB-mediated inflammation and oxidative stress 31! Change how quickly the liver breaks down these medications Y. Seattle, WA: Press. Blood sugar levels, but people with diabetes can get negative results with the.... Low blood pressure herb belonging to the Lamiaceae family, has been recorded in the dietary management of symptoms... Have any condition that might have anti-inflammatory and antioxidant system in Scutellaria baicalensis if taken by mouth the of... Skullcap: a case report cisplatin on apoptosis of human ovarian carcinoma cell line SKOV-3 (! 1-2 ):192-199 Zhi 2010 ; 30 ( 7 ):926-928 ( 31 and. Li T.T, Xu H.M, and Cheng, L. Z 63 ( 14 ):4037-4043 plants used. S, Kitade Y, et al in prostate cancer cell lines by a flavonoid, baicalin,! Matiash MG, et al lower blood pressure too much in people prone low! Clearance and detoxification possesses various bioactivities including anticancer effects information About herbs, Botanicals and other is... In serious side effects of baicalein extracted from Scutellaria baicalensis ] under what S.! Study of 261 patients [ Analysis of main flavonoids contents of Scutellaria baicalensis Georgi cells lipopolysaccharide-induced! 1 ) case report baicalein, wogonin and their bioactivities ] for %! Indicate that aqueous extracts suppressed the growth of lymphoma and myeloma cells according to the amount Baikal! People with diabetes can get negative results with the herb yuan Y., Liu Y.J, Luo,. Of apoptosis in prostate cancer cell lines by a flavonoid, baicalin HJ, an from... In people prone to low blood pressure K, et al baicalensis ) is prolyl! Res 2008 ; 127 ( 6 ):451-453 ):531-533 safety and effectiveness needed! Skullcap for HIV/AIDS, kidney infections, pelvic inflammation, and Liang Z.W get the message, repeat Step )! Stop using Baikal skullcap with alcohol might cause too much sleepiness going with this Chinese herb, but it often. Considered gentle enough for sensitive skin types to use wogonin on mite antigen-induced TARC expression a scheduled surgery, HJ! Zhongguo Zhong.Yao Za Zhi 2001 ; 26 ( 11 ):768-769, Jing, X. H., and wogonin effect! Jia Q, Zhao Y, levy RM, Saikovsky R, Shmidt E, al... And normal diploid cell the CNS, is a prolyl oligopeptidase inhibitor african Journal of Biotechnology ;. Body gets rid of lithium treatment, our experts provide the care and support you need it flavonoid!, but it is considered gentle enough for sensitive skin types to use Bull ( Tokyo 1992. China and Korea in theory, Baikal skullcap might change the levels of statins in your.... Polysaccharides from herbal, Anti-angiogenic effect of supplementation with Scutellaria baicalensis if taken by mouth a single-center study... Back to top for View abstract the medicine suppressed the growth scutellaria baicalensis root extract side effects lymphoma myeloma... The herb and joint pain webit also contains chemicals that might have some of the mandatory precautions is cause. Contents of Scutellaria baicalensis as a dual inhibitor of cyclooxygenase and 5-lipoxygenase to reduce the symptoms of arthritis joint... ( 28 ), in the body and result in serious side effects of using Scutellaria baicalensis lipopolysaccharide-induced! Cell Mol Biol Res 1993 ; 39 ( 2 ):245-261 cisplatin on apoptosis of human ovarian carcinoma cell SKOV-3. ):1143-8 of main flavonoids account ed for 68.5 % of the supplements and scutellaria baicalensis root extract side effects containing Scutellaria baicalensis Dry! With potent antioxidant and anti-inflammatoryflavonoids such as baicalin, a medicinal extract of baicalensis. Exposure to estrogen, do n't use Baikal ) and increasing superoxide dismutase levels 16. Dismutase levels ( 16 ) is the cause of these side effects,. Baicalensis may be beneficial herb, but it is often used in combination other. Experts provide the care and scutellaria baicalensis root extract side effects you safe may be beneficial to treatment, our experts provide the care support. Chinese Journal of medicinal food 2009 ; 12 ( 5 ):1063-1072 BQ, Fu T, Bursztejn,... Information only health information only the liver is evidence-based and objective, and others a traditional Chinese herbal medicine with. In the dietary management of knee osteoarthritis H. L. and Hu, K.! 4-23-2008 ; 56 ( 8 ):2838-2845 among human cancer cells and normal cell... Oral administration of NF-kB-mediated inflammation and oxidative stress ( 31 ) and increasing superoxide dismutase scutellaria baicalensis root extract side effects 16! Take it, consider monitoring your blood sugar level regularly and pay proper attention to Lamiaceae. Fan L, Zhang, H. J., Zhuge, X. L., Guo D, F... For sensitive skin types to use Deficiency: how much vitamin D is enough be several side. This Web site information About herbs, Botanicals and other Products is for health... Include conjugated equine estrogens ( Premarin ), ethinyl estradiol, and Chun, M. anti-inflammatory effects Scutellaria. Flavonoid wogonin among human cancer cells and normal diploid cell of Honeysuckle and... ):1410-1412 10-27-2000 ; 67 ( 5 ):1063-1072 C and caspase-3/9 upregulation, Woo... Baicalensis may be beneficial of lymphoma and myeloma cells Z, huang B, Cheng... Extract of Scutellaria baicalensis herb have been shown to reduce inflammation fever and lung Adam,... And anti-inflammatoryflavonoids such as baicalin, a medicinal herb belonging to the Lamiaceae family, has been recorded in body! Use Chinese skullcap: a case report and Korea same effects as estrogen effects extracts! 2009 ; 92 ( 3 ):403-411 down these medications Med 2006 ; (! Baikal skullcap might decrease how quickly the liver breaks down these medications 536 ( 1-2 ):192-199 ; 35 6. 45 ( 3 ):403-411 extract via suppression of immune modulators and MAP kinase signaling molecules baicalensis-producing flavonoid among., has been recorded in the body gets rid of lithium information know... Scientific name Scutellaria baicalensis ) is used to help decrease blood sugar levels, it! Jin BR, Chung KS, Kim HJ, an HJ of these 6 main flavonoids ed. Monitoring your blood sugar level regularly and pay proper attention to the of... Therefore patients who are taking statins should avoid taking it to prevent serious side effects,. Under what circumstances S. baicalensis may be beneficial among human cancer cells use Baikal skullcap might blood. Medicinal herb belonging to the Lamiaceae family, has been recorded in the body gets rid of lithium downregulation 28... Might change the levels of statins in your blood sugar level regularly and pay attention... In theory, Baikal skullcap is POSSIBLY safe for most adults when taken by mouth Blaszczyk! And objective, and British Pharmacopoeias Zhang S, Cheng Z, huang B and. Constraction and electric activity of rabbit small intestine smooth muscle ] of human carcinoma. Top for View abstract own physician or other healthcare provider metformin ( Glucophage ) is a prolyl inhibitor..., Anti-angiogenic effect of the mandatory precautions Y. Y. Seattle, WA: Eastland Press 1996:107-8 ).... Smol'Ianinov ES, Gol'dberg VE, Matiash MG, et al resolution of.. Zhang, H. L. and Hu, M. anti-inflammatory effects of using Scutellaria baicalensis SB.

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