It may cause skin irritation or allergy. Though like any other RU58841 product, it is not FDA regulated. and our Small measuring spoon 9. Have not used product long enough but the team here were very helpful and send me an additional order for free when package looked like it had been tampered with, Fast delivery too early to review product, easy to work with, will continue business. Been wondering if there's some composition or form of RU or something to mix it with to make your scalp respond or something. Shedding stopped almost immediately after starting treatment. Other anti-androgenic drugs act by either reducing or blocking the synthesis of dihydrotestosterone (DHT). Read More DHT Blockers for Hair Loss: An In-Depth OverviewContinue. Essentially, to prevent degradation of the compound, you simply must make sure it's stored out of any direct light and it's in a cold enough temperature. Recently I had a delivery issue and Anagenic immediately resent new product to me. Next, pour the 50ml of K&B solution into the beaker with the 2.5 grams of RU58841 raw powder. This website uses cookies to improve your experience while you navigate through the website. Very effective product. He is passionate about all areas of health but has a particular interest in dermatology and skin health, including the treatment of hair loss. For now, information about its side effects can only be derived online from the reviews of customers who have actually used the product. However if you wish to make your own solution without the minoxidil, you can use ethanol to do so. Please Log in or Create an account to join the conversation. Many of the stories published online are claims from individuals who may either have a conflict of interest or are already on other hair-loss medications such as minoxidil and finasteride. RU58841 is a topically applied anti-androgenic substance. This has stopped my hair loss and allow for regrowth. It was renamed after newer companies bought the rights to the original product, RU58841. After dedicating over 8 years to extreme self-improvement, I have created "More Plates More Dates" as a one stop shop for helping you to get yourself on the right path to the "best you" possible too. But based on the physiologic processes it undergoes, we can hypothesize on some of its potential side effects. This non steroidal topical androgen antagonist was investigated for therapeutic value in androgenetic alopecia and acne. DHT Blockers for Hair Loss: An In-Depth Overview, 5 Best LLLT Devices: Laser Treatment for Hair Loss, https://doi.org/10.1016/0960-0760(94)90250-X, https://doi.org/10.1046/j.1365-2133.1997.19382053.x, https://international.kyowa-kirin.com/share/pdf/press-release-prostrakan-rebrands-as-kyowa-kirin-18-04-16.pdf, https://www.infona.pl/resource/bwmeta1.element.elsevier-391c502a-853e-3678-ad3c-1984832583e4/tab/summary, https://www.infona.pl/resource/bwmeta1.element.elsevier-5d8b8e9a-87d8-3665-a251-1f766eb8cef1. Although RU58841 can remain potent in room temperature for a while, I put my mixed solutions into sealable 50ml bottles, and then put the bottles into a container, shut the container so no light can get in, and then put that in the fridge. The idea to develop it was first put forth by a French pharmaceutical company called Roussel Uclaf, way back in the 1970s. We also use third-party cookies that help us analyze and understand how you use this website. I have been researching the product for 3 years with good maintenance research results. For a better experience, please enable JavaScript in your browser before proceeding. If you buy something through a link on this page, we may earn a small commission. Also an idea of what we could expect in terms of results. For more information, please see our But one thing that you should put into account is that your skin always produces a lot of oil called sebum. A list of side effects would be useful. This is out of an abundance of caution, mostly. (30 seconds). Shake and swirl the solution lightly until the RU58841 powder has completely dissolved inside the bottle, and the solution is completely clear. This makes the fridge ideal for the storage of mixed solutions. We have actually verified this by doing an HPLC stability test that showed that there was no significant degradation after 24 months at room temperature. A multi-centre, double-blind, randomised, vehicle-controlled study for a quantitative estimation of hair re-growth in male subjects with androgenetic alopecia treated over 6 month with two ethanolic PSK 3841 solutions (2.5% and 5%). Great customer service and fast delivery. K&B solution is 60% Ethanol, 35% Deionized Water, and 5% K&B Emulsifiers. It is hoped that future studies will document the side effects of using RU58841. Regarding storage, mixed RU58841 solutions should be stored in a fridge, and RU58841 raw powder should be stored in a freezer to last for as long as possible. This is the only solution for hair loss period. Prostraken decided to conduct a phase 3 trial as well, but this never went ahead. Small bottles 6. Cookie Notice New comments cannot be posted and votes cannot be cast. As a result, there are no guarantees that you will get what you see advertised. RU58841 mixed in Kirkland 5% minoxidil 1 /r/tressless, 2023-04-08, 12:59:11 Permalink. Add 2.5 grams of powder to the empty beaker on the scale until you see the scale reading 2.5 grams. Otherwise, the hairs in that region will also grow thicker over a period of time. ANAGENINC WILL IMMEDIATELY DENY ANY ORDER THAT WE FEEL WILL BE USED OUTSIDE OF THE SCOPE OF ITS INTENDED PURPOSE. Make sure to use the TARE function when you've got your small plate on the scale, obviously, this cannot be weighed as part of the RU powder so you'll need to be at 0.000 weight before beginning. Take, for instance, a little drug called RU58841. It blocks androgens from binding, such as DHT. Please if you do will you post them to let us see if this stuff works. It is an effort to improve information available to the users of /r/PEDs and will function as a type of skunkworks as we work on content and collaborate on research. 6 Best Hair Fibers to Effortlessly Conceal Your Hair Loss. In studies and clinical trials RU58841 solution has shown to strongly compete against DHT at the androgen receptor. You now have a bottle of Minoxidil with 50mg of RU58841 per ml of solution. RU58841 mixture tutorial , for educational purposes only.only to show how you make a mixture , author is for nothing responsibleMy new USA certified 99.6 %. It is also known as PSK3841 or HMR3841. Voila. Using latex gloves, now apply the RU-58841 5% liquid across the scalp, especially areas where you can see visible bald patches. Add the products you need to your cart. Here is the reason: RU58841 competitively binds to the receptors of DHT. Been using it for 9 months. Apply to scalp with a dropper or pipette once daily. So how does RU58841 produce its results? RU58841 can be either bought in a pre-made solution or as the raw powder form. Rats and hamsters were the animal models used to test its effectiveness. and our Pre-made solutions of RU58841 should be stored within a tightly closed bottle in a refrigerator. Despite most people giving attention mostly to the topical formulations, studies now show that oral minoxidil could, Read More Oral Minoxidil for Hair Loss: Better than Topical?Continue. Im excited to see what happens by the end of this bottle! CAS No. 2. The material published on hairverse.com is not intended as medical advice, diagnosis, or recommended treatment. Although it had been produced in the 80s, most of the research about its development progressed into the 90s. I will use RU58841daily for life now. However, as there have been no direct human studies for more than a decade, the FDA has not approved it for the management of any condition. Step 1: Measure out 3000mg (3 grams) of RU58841 raw powder per bottle of Minoxidil by weighing it out. This makes vendors mess around with the concentration and purity of the product. By accepting all cookies, you agree to our use of cookies to deliver and maintain our services and site, improve the quality of Reddit, personalize Reddit content and advertising, and measure the effectiveness of advertising. We won't share your information with anyone. Thought we should wait at least 24 hours after rolling. Reddit and its partners use cookies and similar technologies to provide you with a better experience. Been wondering if there's some composition or form of RU or something to mix it with to make your scalp respond or something. By rejecting non-essential cookies, Reddit may still use certain cookies to ensure the proper functionality of our platform. When you look at studies about the stability of other various compounds you can actually also see that a lot of them are perfectly stable for a long time. Mixed Media & Collage Fiber Arts Dolls & Miniatures Collectibles Figurines & Knick Knacks Memorabilia . Most of the purchases for RU58841 can be made online from several of the most popular suppliers like Chemyo, Kane, andAnagen Inc. (1997). Excellent customer service! The concept of RU58841 is quite old. Wasn't a responder to Minoxidil (at least at the temples) but after a month with tretinoin I'm finally seeing some actual results. If you dont already know what RU58841 is, it is a non-steroidal experimental anti-androgen, which is intended for use as a topical treatment for acne and androgenic alopecia (male pattern baldness). AMAZING PRODUCT, GREAT SERVICE. Evaluation of RU58841 as an anti-androgen in prostate PC3 cells and a topical anti-alopecia agent in the bald scalp of stumptailed macaques. It's also still cold enough to offset degradation to a large degree, but not cold enough to cause crystallization of the powder in the solution basically. Please enable JavaScript in your browser to submit the form. Is there a Tretinoin equivalent for RU out there. Therefore androgens dont have the chance to bind and start the chain reaction of androgenetic alopecia and begin the so called miniaturization process. For instance, this is the best time to apply your minoxidil if you are also using it to treat your hair loss. This non steroidal topical androgen antagonist was investigated for therapeutic value in androgenetic alopecia (pattern baldness) and acne. That is the reason why we occasionally hear of a new research drug promising superior efficacy compared to existing hair loss treatment options.One such research drug is RU58841. Uno, H., Ye, F., Imamura, K., Obana, N., & Bonfils, A. By rejecting non-essential cookies, Reddit may still use certain cookies to ensure the proper functionality of our platform. It works for saving your hairline, unlike dutasteride. Once you see that its turned on and at 0 grams, put an empty beaker on the scale. ProStrakan rebrands as Kyowa Kirin. This can only be done when RU is mixed into a solution like Everclear or KB and dissolved completely. Scan this QR code to download the app now. I'm talking the hard bristles. How To Use RU58841 RU58841 is available in liquid or powder form. After the measurement has stabilized, turn the scale back to 0 with the beaker still on it by pressing the Tare button. Would a reliable member not be interested in packaging this up into monthly bundles with a small mark up and shipping to who ever signs up? It was an awesome surprise to witness that there are stil honest business online. the only complaint I have is that liquid has escaped from my tightly tightened bottle if it leans on its side. Ultimately it will be up to you what you find optimal for which type of Minoxidil you use, and what fits into your hair loss prevention protocol and what doesn't. 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